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    Sirolimus

    Skincare

    Sirolimus, also known as rapamycin, is a medication primarily used as an immunosuppressant. However, recent research has revealed its potential as a powerful anti-aging agent for the skin.

    At Beauty by Doctor (BBD), we are at the forefront of utilising this innovative treatment. Our clinics medical director and founder, Dr Phoebe Jones, has observed remarkable skin rejuvenation results in her patients using a specifically compounded Sirolimus cream.

    How Sirolimus Works for Anti-Aging
    Sirolimus works by inhibiting the mTOR (mammalian target of rapamycin) pathway, a cellular signalling pathway involved in various cellular processes, including growth, proliferation, and protein synthesis.
    Research suggests that inhibiting the mTOR pathway can have several anti-aging effects on the skin:

    Reduced Cellular Aging: Sirolimus slows cellular aging and promotes the removal of senescent cells, which contribute to skin aging.
    Increased Collagen Production: Studies have shown that Sirolimus can stimulate collagen synthesis, improving skin elasticity and reducing wrinkles.
    Enhanced Skin Barrier Function: Sirolimus can strengthen the skin's barrier, improving hydration and protecting against environmental damage.

    A study published in the Journal of Clinical and Aesthetic Dermatology found that topical Sirolimus significantly improved participants' skin texture, fine lines, and wrinkles after 12 weeks of use. Another study published in the Journal of Drugs in Dermatology reported similar findings, with participants experiencing improved skin elasticity and hydration.

    Dr Phoebe has been prescribing a custom-compounded Sirolimus 0.2% cream for her patients and has observed significant improvements in skin texture, tone, and overall appearance. The cream is specifically formulated to optimise the delivery and efficacy of Sirolimus for anti-aging purposes.

    It's important to note that Sirolimus cream is a prescription-only medication and will only be administered if the BBD physician deems it suitable for you after a thorough consultation and evaluation of your medical history and skin concerns.


    Is Sirolimus Cream Right for You?
    Sirolimus cream may be a suitable option if you are looking for a non-invasive anti-aging treatment to improve skin texture, fine lines, wrinkles, and overall appearance. However, consulting with a qualified physician is crucial to determine if Sirolimus is right for you.

    Disclaimer: This information is not a substitute for professional medical advice. Always consult with a qualified physician to discuss your skin concerns and determine the most appropriate treatment options.

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